Table 2. Patient and Maternal Characteristics, Details of Delivery, and Prerandomization Transfusions.
| Characteristics | Liberal transfusion threshold (n = 492)a | Restrictive transfusion threshold (n = 521)a |
|---|---|---|
| Gestational age at birth, median (IQR), wk | 26.1 (24.9-27.6) | 26.4 (25.0-27.6) |
| Birth weight, median (IQR), g | 745 (636-900) | 750 (630-890) |
| Birth weight stratum, g, No. (%) | ||
| <750 | 250 (51) | 255 (49) |
| ≥750 | 242 (49) | 266 (51) |
| Head circumference at birth, median (IQR), cm | 23.0 (22.0-24.5) [n = 486] | 23.0 (22.0-24.5) [n = 514] |
| Sex, No. (%) | ||
| Female | 246 (50) | 263 (50) |
| Male | 246 (50) | 258 (50) |
| Singleton, No. (%) | 405 (82) | 407 (78) |
| Age at randomization, mean (SD), d | 2.5 (0.7) | 2.5 (0.7) |
| Maternal age at delivery, mean (SD), y | 30.9 (5.8) [n = 491] | 31.2 (5.9) [n = 520] |
| Any antenatal corticosteroids, No./total (%) | 432/484 (89) | 451/515 (88) |
| No. of completed courses of antenatal corticosteroids, median (IQR) | 1 (0-2) [n = 484] | 1 (0-2) [n = 515] |
| Cesarean delivery, No./total (%) | 441/492 (90) | 456/520 (88) |
| Delayed cord clamping, No./total (%) | 308/492 (63) | 319/519 (61) |
| Intubated at birth, No. (%) | 254 (52) | 264 (51) |
| RBCTs prior to randomization | ||
| Any RBCT before randomization, No. (%) | 121 (25) | 123 (24) |
| No. of RBCTs before randomization, No. (%) | ||
| 0 | 371 (75) | 398 (76) |
| 1 | 95 (19) | 94 (18) |
| 2 | 16 (3) | 26 (5) |
| 3 | 8 (2) | 2 (0.4) |
| 4 | 2 (0.4) | 1 (0.2) |
Abbreviations: IQR, interquartile range; RBCT, red blood cell transfusion.
a
Denominators are as specified in column heads unless otherwise indicated.