Fig. 1.
Changes in innate immune responses are not evident in the cerebellum at post-weaning age in Npc1nmf164 mice. (A) Images from P30 and P90 mice showing IBA1+ microglia cells containing CD68+ phagosomes at the ML. (B) Expression changes of genes associated with the innate immune response comparing Npc1nmf164 mice at P30 (red, n=3) and P90 (blue, n=3) versus WT mice (n=4). *P<0.05, **P<0.01, ***P<0.001. Scale bar: 30 µm.