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. 2020 Aug 12;190:110042. doi: 10.1016/j.envres.2020.110042

Table 4.

Multivariable regression models on the association with epidemic growth of COVID-19.

Variable Ratio unit Model 1
Model 2
Model 3
Adjusted RRR (95% CI) p value Adjusted RRR (95% CI) p value Adjusted RRR (95% CI) p value
Male inhabitant 1% 1.05 (0.92–1.20) 0.473 1.02 (0.95–1.10) 0.587 1.03 (0.95–1.10) 0.485
Inhabitants aged ≥65 years 1% 1.00 (0.95–1.06) 0.949 0.98 (0.93–1.02) 0.350 0.98 (0.94–1.02) 0.403
Urban density 1000 inhabitants/km2 0.95 (0.91–1.00) 0.038* 0.93 (0.90–0.97) <0.001** 0.93 (0.90–0.97) <0.001**
Taxable income 1,000,000 JPY/inhabitant 0.85 (0.52–1.38) 0.512 0.90 (0.64–1.28) 0.556 0.94 (0.66–1.33) 0.719
Health expenditure 1000 JPY/inhabitant 1.00 (0.99–1.01) 0.686 1.00 (1.00–1.01) 0.756 1.00 (1.00–1.01) 0.681
Life expectancy at birth 1 year 1.10 (0.87–1.40) 0.426 1.02 (0.83–1.26) 0.850 1.00 (0.81–1.24) 0.989
Mean temperature 1 °C 1.05 (1.01–1.08) 0.013* 1.04 (1.01–1.08) 0.018* 1.03 (1.00–1.07) 0.048*
Sunshine hours 1 h 1.02 (1.00–1.04) 0.039*
NO2 1 ppb 1.01 (0.99–1.02) 0.468
SPM 1 μg/m3 1.02 (0.99–1.04) 0.144

Values are expressed as ratios of rate ratios (95% CIs) and 2-sided p values. Significant at * p < 0.05, ** p < 0.01. Abbreviations: JPY, Japanese Yen; CI, confidence interval; RRR, ratio of rate ratio; NO2, nitrogen dioxide; SPM, suspended particulate matter.