Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 12;12(1):e12095. doi: 10.1002/dad2.12095

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Biomarkers at baseline and in the longitudinal study. A, CSF Aβ. Lope (Dementia due to AD: –0.045, MCI due to AD: –1.26, Preclinical AD: –0.126, Healthy controls: –2.00, P = .617). B, CSF t‐tau. Lope (Dementia due to AD: 1.45, MCI due to AD: 2.93, Preclinical AD: 3.63, Healthy controls: 1.07, P =.558). C, CSF p‐tau. Lope (Dementia due to AD: 3.03, MCI due to AD: 3.94, Preclinical AD: 3.36, Healthy controls: 1.40, P =.458). D, Amyloid imaging (SUVR). Lope (Dementia due to AD: 0.009, MCI due to AD: 0.008, Preclinical AD: 0.010, Healthy controls: 0.003, P < .01). E, CMRgl (FDG‐PET). Lope (Dementia due to AD: –0.06, MCI due to AD: –0.03, Preclinical AD: –0.02, Healthy controls: ‐0.01, P < .01. F, Hippocampus. Lope (Dementia due to AD: –139.88, MCI due to AD: –98.12, Preclinical AD: –67.23, Healthy controls: –47.25, P =.02. G, Composite Memory. Lope (Dementia due to AD: –0.23, MCI due to AD: –0.16, Preclinical AD: –0.04, Healthy controls: –0.01, P < .01. H, CDR‐SB. Lope (Dementia due to AD: 1.8, MCI due to AD: 0.70, Preclinical AD: 0.15, Healthy controls: 0.06, P < .01). Aβ, amyloid beta; AD, Alzheimer's disease; CDR‐SB, Clinical Dementia Rating scale Sum of Boxes; CMRgl, cerebral metabolism rate for glucose on FDG‐PET (fluorodeoxyglucose‐positron‐emission tomography); CSF, cerebrospinal fluid; MCI, mild cognitive impairment; SUVR, standard uptake value ratios on amyloid imaging;.