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The trajectories of biomarkers in sporadic Alzheimer's disease. CDR‐SB, Clinical Dementia Rating scale Sum of Boxes; CMRgl, cerebral metabolism rate for glucose on FDG‐PET (fluorodeoxyglucose‐positron‐emission tomography); CSF, cerebrospinal fluid; SUVR, standard uptake value ratios on amyloid imaging. Composite memory is a weighted score based on memory items in Rey Auditory Verbal Learning Test, the Alzheimer's Disease Assessment Scale‐Cognitive, the MMSE and Logical Memory.
