Table 3.

Comparison of PINP and β-CTX levels between the two groups before and after the treatment.

	N	Before treatment	After treatment
			1 months	6 months	12 months
P1NP
ZOL	121	38.85 ± 2.01	28.77 ± 1.89	14.79 ± 1.01∗	16.53 ± 5.23∗∗
Conservative	121	39.76 ± 2.76	34.12 ± 5.41	32.11 ± 4.71	32.76 ± 2.31
β-CTX
ZOL	121	0.47 ± 0.02	0.37 ± 0.01	0.19 ± 0.01∗	0.27 ± 0.06∗∗
Conservative	121	0.48 ± 0.01	0.45 ± 0.02	0.44 ± 0.04	0.45 ± 0.04

^∗ P < 0.05 ZOL group vs conservative group 6 month after treatment; ^∗∗P < 0.05 12 months after treatment.