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. 2020 Aug 1;2020:3598715. doi: 10.1155/2020/3598715

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Copyright © 2020 Yintao Zhao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FSTL1 overexpression attenuated DOX-induced damage in vitro. (a, b) Nrf2 expression and Nrf2 activity in NRCMs (n = 6). (c) Nrf2 expression after siRNA infection (n = 6). (d) ROS production in NRCMs (n = 6). (e) The mRNA levels of SOD1 in NRCMs (n = 6). (f) The level of 4-HNE in NRCMs (n = 6). (g, h) Caspase 3 activity and LDH release (n = 6). (i) Cell viability (n = 6). ^∗P < 0.05. For (c), the data were analyzed using two-tailed Student's t-tests. For the others, the data were analyzed using one-way ANOVA, followed by Tukey's post hoc analysis.