Table 3. . Minimal bactericidal concentration assay for compounds 2b, 5, 4f, 6c and 6f.
Compound | MIC (μM) | MBC (μM) | Concentration dependent | Time dependent |
---|---|---|---|---|
2b† | 92 | >200 | ND | ND |
4f† | 58 | 100 | N | Y |
5 | >50 | >50 | ND | ND |
6c† | 56 | 100 | Y | N |
6f† | 18 | 50 | Y | N |
Values indicate that compounds have a very good activity.
MBC: Minimal bactericidal concentration; MIC: Minimum inhibitory concentration; N: No; ND: Not determined; Y: Yes.