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| Compound | Test species | Mean plasma fraction unbound (%) | Mean plasma fraction bound (%) | Recovery |
|---|---|---|---|---|
| 6f | Human | 7.8 | 92.2 | 24.5 |
| Propranolol† | Human | 20.7 | 79.3 | 93 |
| Warfarin† | Human | 0.51 | 99.5 | 96.7 |
Control compounds: propranolol (normal binding) and warfarin (high-binding).
