Table 9. . Results of Caco-2 assay of compound 6f.

Compound	Mean A→B Papp† (10-6cm/s)	Mean B→A Papp† (10-6cm/s)	Efflux ratio‡
6f	0.47	0.095	0.20
Atenolol§	0.13	0.37	2.8
Propranolol§	12.7	25	2
Talinolol§	0.077	3.3	43

^†Papp is the apparent permeability;

^‡Efflux ratio (Re) is P_app (B→A)/P_app (A→B);

^§Control compounds.