Table 2.
Association between trauma variables, PTSD and GrimAge acceleration.
| GTP (Discovery cohort) | DNHS (Replication cohort) | |||||||
|---|---|---|---|---|---|---|---|---|
| Beta | SE | t value | p value | Beta | SE | t value | p value | |
| Trauma burden | 0.12 | 0.06 | 2.13 | 0.03 | 0.13 | 0.07 | 1.87 | 0.06 |
| Childhood trauma | 0.19 | 0.37 | 0.51 | 0.61 | −0.65 | 0.85 | −0.76 | 0.44 |
| Current PTSDa | 0.86 | 0.38 | 2.25 | 0.02 | NA | NA | NA | NA |
| Lifetime PTSDb | 0.87 | 0.31 | 2.80 | 0.005 | 1.38 | 0.67 | 2.04 | 0.04 |
SE standard error
Results are from multiple regression, controlling for sex, array type and cell proportions of CD4T, CD8T, NK, B cell, mono. Significant effects are shown in bold.
aData not available for DNHS cohort.
bAssessed by CAPS in GTP, and by PCL-C in DNHS.