Table 2.
Univariate | Multivariate (FISH abnormalities only) | Multivariate (all) | ||||
---|---|---|---|---|---|---|
RR (95% CI) | P | RR (95% CI) | P | RR (95% CI) | P | |
+1q | 1.9 (1.6-2.3) | <.001 | 1.7 (1.5-2.1) | <.001 | 1.5 (1.2-1.8) | <.001 |
HR IgH translocation | 2.0 (1.7-2.5) | <.001 | 1.5 (1.2-1.9) | <.001 | 1.9 (1.5-2.4) | <.001 |
Del(17p) | 2.0 (1.6-2.5) | <.001 | 1.9 (1.5-2.3) | <.001 | 1.6 (1.2-2.0) | <.001 |
Monosomy 13 | 1.4 (1.2-1.7) | <.001 | 1.2 (1.0-1.4) | .09 | — | — |
ISS stage (3 vs 1/2) | 1.9 (1.6-2.3) | <.001 | — | — | 1.8 (1.4-2.1) | <.001 |
Age ≥70 y | 2.1 (1.8-2.5) | <.001 | — | — | 2.3 (1.9-2.8) | <.001 |
OS univariate and multivariate analyses including +1q, HR IgH translocation, del(17p), monosomy 13, advanced ISS stage, and old age.