Table 6.
Selected univariable and multivariable analysis for aGVHD grade 3-4
| Factors | SHR | 95% CI | P |
|---|---|---|---|
| Univariable analysis for aGVHD grade 3-4 | |||
| B-ME Ab GVH | 1.09 | 1.01-1.19 | .034 |
| B-ALL ME GVH | 1.04 | 0.99-1.09 | .052 |
| Class I-Ab ME GVH | 1.06 | 0.99-1.14 | .063 |
| Class I-ALL ME GVH | 1.02 | 0.99-1.06 | .119 |
| DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 1.12 | 0.45-3.28 | .708 |
| Nonpermissive mismatch GVH | 1.00 | 0.27-3.74 | .995 |
| Nonpermissive mismatch HVG | 1.24 | 0.28-5.41 | .768 |
| Multivariable analysis for aGVHD grade 3-4* | |||
| B-ALL ME GVH (continuous) | 1.05 | 1.01-1.12 | .036 |
| Class I-Ab ME GVH (continuous) | 1.09 | 1.00-1.18 | .041 |
| DPB1-Ab ME GVH (continuous) | 0.78 | 0.65-1.02 | .112 |
*Impact of HLA eplet mismatch on each locus on aGVHD grade 3-4 was analyzed in separate models, adjusted for sex, age, HCT-CI, DRI, transplant protocol, conditioning regimen intensity, donor relation, stem cell source, and ABO match. Impacts of these covariates are not shown.