Figure 2.

Baseline factors associated with symptom and spleen response to JAKis. (A) The results of univariate (top) and multivariate (bottom) logistic regression analyses of baseline factors predictive of symptom response at 6 months according to the revised IWG-MRT/ELN²³ in 61 patients with MF treated with JAKis. (B) The results of univariate (top) and multivariate (bottom) logistic regression analyses of baseline factors predictive of spleen response at 6 months according to the revised IWG-MRT/ELN³ in 61 patients with MF treated with JAKis. Firth’s logistic regression method was used to cope with the bias of maximum likelihood estimates. BL, baseline; LCM, left costal margin; MF-RUXO time interval, time interval between myelofibrosis diagnosis and initiation of JAKis.