Table 2.
Comparison of long vs. short follow-up cohorts: METABRIC (largest dataset, long follow-up) vs. TCGA and MSK (combined smaller datasets, short follow-up). Significant difference was found with respect to age and tumor size, but not tumor grade or LN status. Table excludes “unknown” cases for each variable
| METABRIC (N = 702) | TCGA AND MSK (N = 878) | χ2 test | ||||
|---|---|---|---|---|---|---|
| N | % | N | % | |||
| Age | < 50 years | 125 | 17.8 | 277 | 31.5 | p < 0.00001 |
| ≥ 50 years | 577 | 82.2 | 601 | 68.5 | ||
| Tumor size | < 20 mm | 215 | 30.6 | 426 | 48.5 | p < 0.00001 |
| ≥ 20 mm | 487 | 69.4 | 452 | 51.5 | ||
| Tumor grade | 1–2 | 405 | 60.2 | 481 | 56.6 | p = 0.158 |
| 3 | 268 | 39.8 | 369 | 43.4 | ||
| LN status | Negative | 370 | 53.9 | 489 | 55.8 | p = 0.457 |
| Positive | 316 | 46.1 | 387 | 44.2 | ||