Table 2.

Relationship between POLE2 expression and tumor characteristics in patients with esophagus cancer

Features	No. of patients	POLE2 expression			P value
		Low		High
All patients	101	41		60
Age (years)					0.601
≤ 65	51	22		29
> 65	50	19		31
Gender					0.040*
Male	75	26		49
Female	26	15		11
Lymph node positive					0.100
≤ 1	52	24		28
> 1	38	11		27
Tumor size (cm)					0.757
< 5	41	16		25
≥ 5	42	15		27
Grade					0.635
I	8	3		5
II	66	26		40
III	27	12		15
AJCC stage					0.002**
1	4		2	2
2	42		25	17
3	50		13	37
T infiltrate					0.623
T1	4		2	2
T2	11		5	6
T3	80		33	47
T4	3		1	2
Lymphatic metastasis (N)					0.006**
N0	45		26	19
N1	30		7	23
N2	19		6	13
N3	4		1	3