Table 3.
Baseline characteristics of hepatitis B virus-associated acute-on-chronic liver failure patients enrolled in Study 2, n (%)
| Characteristic | Nutritional support | None-nutritional support | P value |
| n | 234 | 207 | |
| Age (yr) | 46.7 ± 10.8 | 47.5 ± 11.6 | 0.454 |
| Male | 202 (86.3) | 172 (83.9) | 0.345 |
| HBeAg positive | 98 (41.9) | 96 (46.4) | 0.342 |
| HBV-DNA (log10 IU/mL) | 6.14 (1.85, 8.13) | 6.54 (1.53, 8.71) | 0.097 |
| PLT (109/L) | 120.2 ± 49.1 | 112.6 ± 52.6 | 0.117 |
| ALT (IU/L) | 680 (421, 1191) | 652 (447, 1352) | 0.243 |
| AST (IU/L) | 592 (313, 980) | 613 (320, 1014) | 0.381 |
| ALB (g/L) | 33.6 ± 4.9 | 34.1 ± 5.2 | 0.299 |
| TBIL (µmol/L) | 274.1 (166.1, 588.7) | 291.5 (162.5, 604.3) | 0.227 |
| PTA (%) | 34 (14, 40) | 32 (11, 40) | 0.135 |
| INR | 2.46 ± 0.18 | 2.49 ± 0.21 | 0.107 |
| BUN (mmol/L) | 6.1 (3.1, 8.7) | 6.4 (3.2, 9.2) | 0.295 |
| Cr (μmol/L) | 73 (66, 104) | 76 (59, 98) | 0.530 |
| SBP | 124 (53.0) | 106 (51.2) | 0.708 |
| Hepatic encephalopathy | 97 (41.5) | 82 (39.6) | 0.695 |
| Hepatorenal syndrome | 24 (10.3) | 19 (9.2) | 0.703 |
| MELD scores | 25.4 ± 4.8 | 26.1 ± 5.2 | 0.142 |
| Artificial extracorporeal liver support | 141 (60.3) | 124 (59.9) | 0.940 |
Data presented as mean ± SD, median (IQR) or n (%). ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; Cr: Creatinine; HBeAg: Hepatitis B e antigen; INR: International normalized ratio; SBP: Spontaneous bacterial peritonitis; MELD: Model for end-stage liver disease; PLT: Platelet; PTA: Prothrombin activity; TBIL: Total bilirubin level.