Table 1.
General characteristics of the subjects for analysis on obesity-related differentially methylated CpGs
| Phase I: Discovery/population | Phase II: Replication 1/population | Phase III: Replication 2/hospital | Childhood obesity | |||||
| Lean | Obese* | Lean | Obese† | Lean | Obese† | Lean | Obese* | |
| N | 250 | 200 | 240 | 133 | 46 | 29 | 46 | 48 |
| Gender (male) | 250 (100%) | 200 (100%) | 240 (100%) | 133 (100%) | 18 (39%) | 11 (38%) | 46 (100%) | 48 (100%) |
| Age (years) | 47.2±5.9 | 47.7±5.9 | 61.0±8.8 | 56.9±7.5 | 58.2±14.4 | 55.9±11.2 | 14.0±0.8 | 13.9±0.8 |
| BMI (kg/m2) |
21.4±1.1 | 31.6±1.6 | 21.4±1.1 | 28.5±1.4 | 20.8±1.4 | 30.3±3.0 | 19.7±1.4 | 34.8±3.7 |
*BMI>30 kg/m2.
†BMI>27 kg/m2.
BMI, body mass index.