Table 1.
The Basic Characteristics of MDR/XDR Acinetobacter baumannii patients
| Characteristics n (%) |
Survivors 72 (70.59) |
Nonsurvivors 30 (29.41) |
Odds Ratio (95%CI) |
P value | |
|---|---|---|---|---|---|
| Age, mean ± SD, month | 30 (9.6, 88.75) | 42 (9.825, 102.75) | 0.691 (−29.63, 12.02) | 0.404 | |
| Male/Female (n=) | 44/28 | 19/11 | (0.286,0.478) | 0.835 | |
| Underlying disorders | Pneumonia n (%) | 61 (84.7) | 25 (83.3) | 0.902 (0.284,2.862) | 0.862 |
| Meningitis n (%) | 1 (1.38) | 6 (20) | 17.75 (2.033,154.993) | < 0.001* | |
| Leukemia/Solid tumor n (%) | 6 (8.33)/10 (13.89) | 6 (20)/11 (33.3) | 4.577 (1.84, 51.383) | < 0.001 | |
| Trauma n (%) | 3 (4.17) | 0 (0) | 0.557 (0.547, 0.567) | 0.553 | |
| Sepsis n (%) | 65 (90.27) | 25 (83.33) | 0.538 (0.156, 1.855) | 0.321 | |
| Peritonitis n (%) | 8 (11.11) | 8 (26.67) | 2.909 (0.975, 8.68) | 0.049 | |
| Cardiovascular disease n (%) | 8 (11.11) | 5 (16.67) | 1.35 (0.401, 0.454) | 0.627 | |
| Hepatic disorder n (%) | 5 (6.94) | 2 (6.67) | 0.814 (0.149, 4.462) | 0.813 | |
| Others n (%) | 10 (13.89) | 5 (16.67) | 1.24 (0.385, 3.994) | 0.718 | |
| WBC count(*109/L) | M(Q1,Q3) | 7.99 (5.81, 13.62) | 5.1 (1.64, 14.78) | 0.046 | |
| Neutropenia(*109/L) | M(Q1,Q3) | 4.88 (3.51, 9.1) | 3.37 (0.61, 11.05) | 0.158 | |
| CRP (mg/L) | M(Q1,Q3) | 37 (10, 74) | 27 (16, 94.5) | 0.406 | |
| PCT (ng/L) | M(Q1,Q3) | 0.48 (0.18, 5.08) | 1.56 (0.53, 8.27) | 0.066 | |
| Lactate (mmol/L) | mean ± SD | 3.12 ± 2.9 | 3.09 ± 2.42 | 0.955 | |
| PRISM III | mean ± SD | 6.73 ± 5.19 | 8.3 ± 4.76 | 0.183 | |
| Shock | n (%) | 18, 25% | 16, 53.33% | 3.429 (1.403, 8.382) | 0.006* |
| PaO2/FiO2 | mean ± SD | 269 ± 113.55 | 220.96 ± 150.16 | 0.139 | |
| Exposure factors | |||||
| Steroid n (%) | 49 (68.06) | 21 (70) | 1.619 (0.662, 3.963) | 0.289 | |
| Immune suppressor n (%) | 11 (15.27) | 8 (26.67) | 2.017 (0.718, 5.665) | 0.263 | |
| Length of hospital day (day,M(Q1,Q3)) | 24 (14, 48.75) | 31.5 (24.75, 41.5) | 0.605 | ||
| Length of PICU day (day,M(Q1,Q3)) | 14 (8,23.5) | 22.5 (13.25, 41) | 0.459 | ||
| Length of broad-spectrum antibiotic therapy (day,M(Q1,Q3)) | 22 (12, 43) | 31.5 (24.75, 41.5) | 0.123 | ||
| Length of mechanical ventilation (day, M(Q1,Q3)) | 6 (1, 15) | 10 (6, 25) | 0.02 | ||
| Length of CRRT/ECMO(h, M(Q1,Q3)) | 0 (0, 0) | 0 (0, 6) | 0.02 | ||
| Central vein catheter n (%) | 69 (95.83) | 30 (100) | 1.435 (1.26, 1.634) | 0.256 | |
|
Arterial catheter n (%) |
58 (80.56) | 29 (96.67) | 7.0 (0.877, 55.872) | 0.036 | |
| Intra trachea intubation n (%) | 57 (79.17) | 29 (96.67) | 7.632 (0.96, 60.662) | 0.027 | |
| Operation n (%) | 31 (43.06) | 20 (66.67) | 2.645 (1.085, 6.448) | 0.03 |
*p < 0.01