Table 2.

Absolute changes from baseline in serum sclerostin, P1NP and CTx stratified for each intervention group

	Placebo		Prednisolone 7.5 mg		Prednisolone 30 mg
	Change	p	Change	p	Change	p
Serum sclerostin (pg/mL)	1.5 [−6.5 to 20] (+1.5%)	0.509	‐1 [−26.25 to 16.5] (−0.9%)	0.637	−8.5 [−28 to 7.25] (−7.9%)	0.033
Serum P1NP (μg/L)	−1.5 [−15.25 to 11.25] (−2.2%)	0.569	−9 [−24 to −1.25] (−11.0%)	0.002	−28 [−39.25 to −18.25] (−38.9%)	0.001
Serum CTx (ng/L)	64 [−24.25 to 120] (+11.1%)	0.198	82 [−54.5 to 139.8] (+13.5%)	0.168	108 [55 to 177] (+20.0%)	0.002

Data represent absolute change from baseline expressed as medians (interquartile range) and percentages.

p, after treatment versus baseline within each intervention group.