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. 2020 Aug 12;25(10):1822–1838. doi: 10.1016/j.drudis.2020.08.002

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© 2020 Elsevier Ltd. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Schematic presentation of the mechanism of action of chloroquine, hydroxychloroquine, umifenovir, lopinavir, ritonavir, remdesivir, favipiravir, ribavirin, tocilizumab, and sarilumab against Coronavirus 2019 (COVID-19). Abbreviations: IL, interleukin; SARS-CoV-2, Severe Acute Syndrome Coronavirus 2; TMPRSS2, Transmembrane Protease Serine 2.