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Drug categorization based on mechanism of action
| Category I: inhibit RNA-dependent RNA Pol | Category II: bind ACE2 receptor and increase endosomal pH | Category III: inhibit SARS-COV-2 main protease | Category IV: prevent interaction of S protein with ACE2 | Category V: bind IL-6R | Category VI: inhibit TMPRSS2 |
|---|---|---|---|---|---|
| Remdesivir, favipiravir, ribavirin | HCQ, CQ | Lopinavir, ritonavir (inhibits CYP450-3A4) | Umifenovir | Tocilizumab, sarilumab | Camostat |
