Table 3.

Summary of biosynthetic gene cluster (BGC) potential of medicinal plant endophytic bacteria. AntiSMASH was used to predict BGCs in the 26 whole-genome sequenced endophytic isolates. The predicted BGCS were curated and de-replicated to determine the number of distinct BGCs in the genome collection.

				Specialised metabolite class
Genus	Number of genomes	AntiSMASH predicted BGCs	Distinct BGCs	NRPS	Bacteriocin	T3PKS	NRPS-T1PKS	T1PKS	Thiopeptide	Lassopeptide	Lantipeptide	Terpene	Phosphonate	Arylpolyene	Butyrolactone	Homoserine lactone	Microcin	Siderophore	Other
Bacillus	9	67	34	7	5	1	1	0	1	2	5	5	1	0	0	0	0	3	3
Klebsiella	4	17	6	1	1	0	1	0	1	0	0	0	0	0	1	0	1	0	0
Enterobacter	3	15	6	1	0	0	0	0	1	0	0	0	0	1	1	1	0	1	0
Serratia	2	33	10	4	1	1	2	0	1	0	0	0	0	0	0	1	0	0	0
Curtobacterium	2	12	8	0	0	2	0	0	0	0	0	1	0	0	0	0	0	1	4
Acinetobacter	1	6	7	2	1	0	0	0	0	0	0	0	0	2	0	1	0	1	0
Aureimonas	1	4	4	0	0	0	0	1	1	0	0	2	0	0	0	0	0	0	0
Methylobacterium	1	8	8	0	0	0	0	1	0	0	0	3	0	0	0	2	0	0	2
Pantoea	1	11	9	2	1	0	0	0	1	0	0	2	0	2	0	1	0	0	0
Pseudomonas	1	18	6	2	1	0	0	0	0	0	0	0	0	0	1	1	0	0	1
Stenotrophomonas	1	4	4	1	2	0	0	0	0	0	0	0	0	1	0	0	0	0	0
Total	26	195	102	20	12	4	4	2	6	2	5	13	1	6	3	7	1	6	10

BGC, biosynthetic gene cluster; NRPS, nonribosomal peptide synthase; T1PKS, Type 1 polyketide synthase; T3PKS, Type 3 polyketide synthase; NRPS-T1PKS, nonribosomal peptide synthase-Type 1 polyketide synthase hybrid