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PnPP-19 reduces IOP in rats with ocular hypertension. Comparison between treated hypertensive eyes with Vehicle (saline – NaCl 0.9%), PnPP-19 (80 µg/eye), Bimatoprost (8.8 µg/eye), PnPP-19 + Bimatoprost (PnPP-19 at 80 µg/eye plus Bimatoprost at 8.8 µg/eye) and healthy eyes. Results expressed in mm Hg (N = 6). Asterisks represent statistical difference in relation to the untreated * P < 0.5; ** P < 0.01; *** P < 0.001, 2-way ANOVA with Bonferroni post-test.
