Figure 2.

MSC treatment in EAE mice preserves Pattern-ERG amplitude. (A) The latency (L) was measured as the time from presentation of the stimulus to the P1 peak and the PERG amplitude (A) was determined as the distance from the P1 peak to the N2 trough. (B) Thirty-two days after induction, sham-immunized controls and MSC-treated EAE mice show almost identical PERG amplitudes, whereas untreated EAE mice demonstrate a significantly declined amplitude. This result indicates a robust MSC-related rescue effect on RGC function.