Table 1.
Summary of Performance Between High-Risk Human Papillomavirus (HR-HPV) RNA and DNA In Situ Hybridization (ISH)
| Performance Factor | No. of Responses | Correct No. (%) | P Valuea |
|---|---|---|---|
| ISH type | <.001 | ||
| RNA | 462 | 450 (97.4) | |
| DNA | 806 | 650 (80.6) | |
| HR-HPV copies/cell | |||
| Negative for HR-HPV | .99 | ||
| RNA | 117 | 116 (99.1) | |
| DNA | 203 | 199 (98.0) | |
| 1–2 copies/cell | <.001 | ||
| RNA | 126 | 120 (95.2) | |
| DNA | 240 | 129 (53.8) | |
| 50–100 copies/cell | <.001 | ||
| RNA | 89 | 89 (100.0) | |
| DNA | 156 | 119 (76.3) | |
| 300–500 copies/cell | .99 | ||
| RNA | 130 | 125 (96.2) | |
| DNA | 207 | 203 (98.1) | |
a
Boldface indicates statistical significance.