. 2020 Aug 12;15(8):e0237269. doi: 10.1371/journal.pone.0237269

Table 1. Individual covariate impact on Latino prevalence and disparities (maximum N = 775 counties).

			Latino HIV Prevalence			Disparity
Category	Variable	N	Beta	Std^† Beta	p-value	Beta	Std^† Beta	p-value	Role of Factor
HIV Characteristics	County Prevalence Rate^β	775	0.74	0.54	< 0.001^*	0	0.01	0.98	Homogeneous
	Male Prevalence Rate^β	730	0.74	0.52	< 0.001^*	-0.04	-0.02	0.3	Homogeneous
	Female Prevalence Rate^β	730	0.28	0.27	< 0.001^*	-0.09	-0.08	< 0.001^*	Effect Modifier
	% MSM	730	-0.02	-0.18	< 0.001^*	-0.01	-0.17	< 0.001^*	Effect Modifier
	% IDU	656	0.02	0.19	< 0.001^*	0.02	0.17	< 0.001^*	Effect Modifier
	% Heterosexual	744	0	-0.02	0.35	0	0.03	0.31
	New Diagnosis Rate^β	549	0.11	0.16	< 0.001^*	-0.05	-0.08	0.01^*	Effect Modifier
	IDU Prevalence Rate^β	656	0.47	0.45	< 0.001^*	0.05	0.05	0.05	Homogeneous
	MSM Prevalence Rate^β	774	0.73	0.51	< 0.001^*	-0.08	-0.05	0.02^*	Effect Modifier
Socioeconomic	Median Household Income^β	775	-0.52	-0.13	< 0.001^*	0.03	0.01	0.79	Homogeneous
	GINI Index	775	0.04	0.14	< 0.001^*	-0.02	-0.06	0.00^*	Effect Modifier
	% High School Education	775	0.01	0.04	0.1	0.02	0.14	< 0.001^*	Effect Modifier
	% Unemployed	775	0.01	0.02	0.49	-0.02	-0.03	0.19
	Income Inequality Ratio^β	775	0.97	0.14	< 0.001^*	-0.35	-0.05	0.02^*	Effect Modifier
	Non-White/White Segregation Index	775	0.01	0.1	< 0.001^*	0	0.05	0.04	Homogeneous
	Black/White Segregation Index	754	0	0.02	0.5	0	-0.01	0.74
	% Non-Latino White Living Below Poverty	75	0.03	0.14	< 0.001^*	0.01	0.05	0.05	Homogeneous
	% Living Below Poverty	775	0.02	0.14	< 0.001^*	0	-0.02	0.33	Homogeneous
Community Environment	% Single Parent Household	775	0.02	0.2	< 0.001^*	0	-0.01	0.52	Homogeneous
	Social Association Rate	775	0.13	0.05	0.07	0.24	0.08	< 0.001^*	Effect Modifier
	Violent Crime Rate	767	0.09	0.06	0.02^*	-0.25	-0.16	< 0.001^*	Effect Modifier
	% Severe Housing Problems	775	0.02	0.09	< 0.001^*	-0.03	-0.15	< 0.001^*	Effect Modifier
	% Rural	775	0	0.03	0.4	0.01	0.16	< 0.001^*	Effect Modifier
Health Behaviors	% Excessive Drinking	775	-0.01	-0.04	0.08	0	-0.01	0.75
	Chlamydia Rate^β	775	0.21	0.12	< 0.001^*	-0.05	-0.03	0.18	Homogeneous
	Drug Overdose Mortality Rate^β	706	-0.02	-0.01	0.73	-0.12	-0.05	0.01^*	Effect Modifier
	Gonorrhea Rate^β	775	0.12	0.11	< 0.001^*	-0.08	-0.07	0.00^*	Effect Modifier
Access to Health Care	% Uninsured	775	-0.03	-0.15	< 0.001^*	-0.06	-0.28	< 0.001^*	Effect Modifier
	Primary Care Provider Rate^β	774	0.03	0.02	0.51	-0.05	-0.03	0.2
	Mental Health Provider Rate^β	771	0.14	0.12	< 0.001^*	0	0	0.92	Homogeneous
	Preventable Hospitalization Rate^β	774	-0.1	-0.03	0.25	-0.24	-0.07	0.00^*	Effect Modifier
	Healthcare Costs^β	775	-0.81	-0.11	< 0.001^*	-0.95	-0.13	< 0.001^*	Effect Modifier
Latino Characteristics	Latino Population % Change 2000–2014	774	-0.05	-0.05	0.04	0.1	0.1	< 0.001^*	Effect Modifier
	% Mexican	775	-0.01	-0.21	< 0.001^*	0	-0.1	< 0.001^*	Effect Modifier
	% Puerto Rican	775	0.01	0.17	< 0.001^*	0.01	0.13	< 0.001^*	Effect Modifier
	% Latino	775	-0.01	-0.14	< 0.001^*	-0.01	-0.23	< 0.001^*	Effect Modifier
	% Not English Proficient	775	-0.02	-0.05	0.02^*	-0.05	-0.17	< 0.001^*	Effect Modifier
	% Latino Living Below Poverty	775	0.01	0.09	< 0.001^*	0.01	0.09	< 0.001^*	Effect Modifier
Latino/Non-Latino White Ratios	Poverty Ratio (% Latino / % Non-Latino White) ^β	775	-0.13	-0.06	0.01^*	0.03	0.01	0.59	Homogeneous
	Population Ratio (% Latino / % Non-Latino White) ^β	775	-0.13	-0.16	< 0.001^*	-0.26	-0.3	< 0.001^*	Effect Modifier
	Income Ratio (% Latino / % Non-Latino White) ^β	766	-0.22	-0.04	0.05	-0.2	-0.04	0.05

^†Std = standardized.

^β Denotes log transformation of variable.

* Denotes significance using a False Discovery Rate (FDR) of 5%.