Table 6. Manually curated biologically relevant putative interactors from sexual reproduction search results.

Protein families within clusters containing query HOGs are listed with their pertinent annotation and literature. GO enrichment results of clusters containing one or more queries were analyzed manually. Full enrichment results are available as S5 Data.

Cluster	Result	GO Term	Citation
REC8	NSE4	GO:0030915 Smc5-Smc6 complex	[54]
SPC72	MID2	GO:0000767 cell morphogenesis involved in conjugation	[55]
SPO71	LES2	GO:0031011 Ino80 complex	[56,57]
SHC1, SPO16	POG1	GO:0000321 re-entry into mitotic cell cycle after pheromone arrest	[58,59]