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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun 10;1864(10):1396–1411. doi: 10.1016/j.bbalip.2019.05.014

Fig. 5.

Fig. 5.

Wy treatment alters hepatic expression of genes involved in BA synthesis, conjugation, and transport. A. mRNA levels of genes involved in BA synthesis in chow- and Wy-treated Ppara+/+ and Ppara−/− mice. B. mRNA levels of genes involved in BA synthesis in chow- and Wy-treated Pparafl/fl and PparaΔHep mice. C. mRNA levels of genes involved in taurine conjugation in chow- and Wy-treated Ppara+/+ and Ppara−/− mice. D. mRNA levels of genes involved in taurine conjugation in chow- and Wy-treated Pparafl/fl and PparaΔHep mice. E. mRNA levels of genes related to the BA sinusoidal transporters in chow- and Wy-treated Ppara+/+ and Ppara−/− mice. F. mRNA levels of genes related to the BA sinusoidal transporters in chow- and Wy-treated Pparafl/fl and PparaΔHep mice. G. mRNA levels of genes related to the BA canalicular transporters in chow- and Wy-treated Ppara+/+ and Ppara−/− mice. H. mRNA levels of genes related to the BA canalicular transporters in chow- and Wy-treated Pparafl/fl and PparaΔHep mice. Data are presented as mean ± SEM; n = 6/group. *P < 0.05 or **P < 0.01, by one-way ANOVA followed by Tukey’s post-hoc correction.