Table 1.
Serum metabolite ions identified in the negative mode that were significantly increased in Wy-treated Ppara+/+ and Pparafl/fl mice.
| m/z | Rt |
Ppara+/+, Wy |
Pparafl/fl, Wy |
Metabolite | |||||
|---|---|---|---|---|---|---|---|---|---|
| P[1] | P[2] | VIP | P[1] | P[2] | VIP | ||||
| M1 | 514.284 | 10.3 | 0.3218 | −0.1882 | 11.1 | 0.3397 | −0.1139 | 11.4 | TCA |
| M2 | 514.284 | 7.2 | 0.1306 | −0.0751 | 4.6 | 0.1527 | −0.0587 | 5.4 | TβMCA |
| M3 | 391.285 | 18.8 | 0.0677 | −0.0398 | 2.8 | 0.0801 | −0.0095 | 3.4 | DCA |
| M4 | 514.284 | 6.7 | 0.0551 | −0.0338 | 2.0 | 0.0565 | −0.0355 | 2.5 | TαMCA |
| M5 | 498.289 | 13.6 | 0.0522 | −0.0295 | 1.8 | 0.0362 | −0.0170 | 2.4 | TDCA |
| M6 | 407.280 | 12.2 | 0.0499 | −0.0309 | 1.7 | 0.0754 | −0.0206 | 1.7 | CA |
| M7 | 498.288 | 13.0 | 0.0389 | −0.0227 | 1.5 | 0.0415 | −0.0170 | 1.6 | TCDCA |
| M8 | 498.288 | 9.8 | 0.0244 | −0.0150 | 1.1 | 0.0294 | −0.0179 | 1.1 | TUDCA |
| M9 | 498.288 | 10.0 | 0.0213 | −0.0049 | 1.0 | 0.0215 | −0.0208 | 1.0 | THDCA |