Figure 3.

Neural crest migration. The neural crest form at the border of the neural plate (top of the embryo), and then collectively migrate (pink arrow) toward the pharyngeal arches (bottom of the embryo). The green areas correspond to cranial neural crest migration, the yellow to cardiac neural crest migration, and the purple to trunk neural crest migration, which must move over the somites (brown ovals). When they reach the pharyngeal arches, they differentiate into a variety of cell types and contribute to many tissues and organs, including the craniofacial structures, the outflow tract, dorsal root ganglia and the enteric nervous system.