Table 2.
Respiratory mechanics and arterial blood gas.
| Variables | COVID– (n = 10) | COVID+ (n = 13) |
|---|---|---|
| PEEP (cm H2O) | 9 ± 3 | 11 ± 2 |
| VT (ml.kg−1 PBW) | 6.0 ± 0.2 | 6.0 ± 0.0 |
| RR (min−1) | 25 ± 5 | 23 ± 3 |
| Ti/Ttotal (%) | 33 ± 1 | 32 ± 2 |
| PEEPtot,rs (cm H2O) | 11 ± 3 | 12 ± 2 |
| Pplat,rs (cm H2O) | 21 ± 2 | 20 ± 3 |
| ΔPrs (cm H2O) | 10 ± 3 | 8 ± 2a |
| ΔPL (cm H2O) | 8 ± 2 | 5 ± 2a |
| Ers (cm H2O. L−1) | 28 ± 13 | 21 ± 7 |
| Ers > 20 cm H2O. L−1 | 8 (80%) | 5 (38%) |
| EL (cm H2O.L−1) | 22 ± 8 | 14 ± 6a |
| Ecw (cm H2O.L−1) | 6 ± 5 | 7 ± 3 |
| EL/Ers (%) | 81 ± 11 | 65 ± 14a |
| End-inspiratory TPPEl | 17 ± 3 | 13 ± 4a |
| pH | 7.34 ± 0.09 | 7.36 ± 0.10 |
| PaO2/FiO2 (Torr) | 122 ± 41 | 130 ± 28 |
| PaCO2 (Torr) | 48 ± 8 | 46 ± 8 |
| Bicarbonates (mmol.L−1) | 25 ± 6 | 26 ± 4 |
| Lactate (mmol.L−1) | 4.8 ± 4.4 | 1.8 ± 0.5a |
Values are mean ± standard deviation or count(percentage).
COVID− = non-COVID-19 ARDS patients; COVID+ = COVID-19 ARDS patients; ΔPrs = driving pressure of the respiratory system; ΔPL = transpulmonary driving pressure; Ecw = chest wall elastance; EL = lung elastance; Ers = elastance of the respiratory system; FiO2 = inspired fraction of oxygen; PaO2 = oxygen partial pressure in arterial blood; PaCO2 = carbo dioxide partial pressure in arterial blood; PBW = predicted body weight; PEEP = positive end-expiratory pressure; PEEPtot,rs = total PEEP of the respiratory system; Pplat,rs = plateau pressure of the respiratory system; RR = respiratory rate; Ti/Ttotal = ratio of inspiratory time over total time of the respiratory cycle; TPPEl = elastance-derived transpulmonary pressure; VT = tidal volume.
p < 0.05 between groups.