Table 3.
Physical function at baseline, 6 and 12 months.
| Baseline | 6 months | 12 months | 0–6 monthsc | 7–12 monthsd | 0–12 monthse | ||||
|---|---|---|---|---|---|---|---|---|---|
| Adj. Diff. | P valueb | Adj. Diff. | P valueb | Adj. Diff. | P valueb | ||||
| 6-m usual walk (s) | |||||||||
| IMX | 4.2 ± 0.6 | 4.4 ± 0.6 | 4.3 ± 0.6 | −0.03 (−0.2, 0.1) | 0.409 | −0.1 (−0.2, 0.1) | 0.348 | −0.1 (−0.2, 0.1) | 0.121 |
| DEL | 4.2 ± 0.7 | 4.4 ± 0.5 | 4.5 ± 0.6 | ||||||
| 6-m fast walk (s) | |||||||||
| IMX | 3.2 ± 0.5 | 3.1 ± 0.5 | 3.1 ± 0.5 | −0.2 (−0.3, −0.1) | <0.001 | 0.0 (−0.1, 0.1) | 0.789 | −0.2 (−0.3, −0.1) | <0.001 |
| DEL | 3.2 ± 0.6 | 3.3 ± 0.6 | 3.3 ± 0.6 | ||||||
| 6-m backwards tandem walk (s)a | |||||||||
| IMX | 13.2 ± 4.1 | 13.7 ± 4.7 | 12.9 ± 3.9 | −0.6 (−2.2, 1.1) | 0.527 | −0.4 (−1.7, 0.9) | 0.406 | −0.6 (−1.9, 0.7) | 0.643 |
| DEL | 13.9 ± 5.3 | 14.9 ± 7.2 | 14.1 ± 6.1 | ||||||
| 400-m walk (s) | |||||||||
| IMX | 246.8 ± 36.1 | 241.9 ± 37.8 | 245.8 ± 40.4 | −9.7 (−14.8, −4.6) | <0.001 | 9.9 (5.0, 14.8) | <0.001 | 0.5 (−5.5, 6.4) | 0.981 |
| DEL | 258.7 ± 53.8 | 263.7 ± 56.9 | 257.7 ± 57.5 | ||||||
| Stair climb (s) | |||||||||
| IMX | 4.8 ± 1.3 | 4.6 ± 1.3 | 4.7 ± 1.3 | −0.4 (−0.6, −0.2) | <0.001 | 0.4 (0.2, 0.6) | <0.001 | 0.0 (−0.1, 0.2) | 0.712 |
| DEL | 5.0 ± 1.5 | 5.2 ± 1.6 | 4.8 ± 1.4 | ||||||
| Repeated chair rise (s)a | |||||||||
| IMX | 10.7 ± 2.2 | 9.9 ± 1.8 | 9.8 ± 1.7 | −1.0 (−1.4, −0.7) | <0.001 | 0.6 (0.2, 0.9) | 0.001 | −0.2 (−0.6, 0.1) | 0.116 |
| DEL | 11.4 ± 2.9 | 11.4 ± 2.5 | 10.1 ± 2.1 | ||||||
Values are the mean ± SD.
IMX immediate exercise, DEL delayed exercise, Adj. Diff. ANCOVA adjusted mean difference and 95% CI.
aIMX n = 54, DEL n = 49.
bP value based on log transformed data except for 6-m usual walk at 7–12 months.
c6 months adjusted for baseline value.
d12 months adjusted for 6-month value.
e12 months adjusted for baseline value.