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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Heart Lung Transplant. 2020 Feb 13;39(9):880–890. doi: 10.1016/j.healun.2020.02.004

Figure 1.

Figure 1

Variation in circulating biomarkers of inflammation, oxidative stress, and endotoxemia across disease categories (HF Class I, II, III, IV, LVAD, and HT). (A) CRP. (B) IL-6. (C) TNF-α. (D) ET-1. (E) Adiponectin. (F) LPS. (G) sCD14. (H) Isoprostane. All p-values for linear trend across HF Class I – IV < 0.01 and all p-values for any difference across all patient categories < 0.001. Light bars: unadjusted. Dark bars: Adjusted for age, sex, and race/ethnicity. CRP, C-reactive protein; ET-1, endothelin-1; HF, heart failure; HT, heart transplantation; IL-6, interleukin-6; LPS, lipopolysaccharide; LVAD, left ventricular assist device; sCD14, soluble CD14; TNF-α, tumor necrosis factor-α.