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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Heart Lung Transplant. 2020 Feb 13;39(9):880–890. doi: 10.1016/j.healun.2020.02.004

Figure 3.

Figure 3.

(A) Two principle coordinates are plotted, derived from the Bray-Curtis measure of beta diversity, summarizing similarity of gut microbial communities across patient categories. PCoA 1 explains 5.3% and PCoA 2 explains 3.7% of variation in microbial communities. p-value derived from PERMANOVA Adonis test of any difference across category = 0.09. (B) Means values of the first principle coordinate derived from the Bray-Curtis measure of beta diversity across patient category. Light bars: unadjusted. Dark bars: adjusted for age, sex, race/ethnicity, and antibiotic use. p-value for any difference across patient category <0.0001. The p-value for linear trend among patients with HF < 0.0001. HF, heart failure; HT, heart transplantation, LVAD, left ventricular assist device; PCoA, principal coordinates analysis; PERMANOVA, permutational multivariate analysis of variance.