Table 3.

Change in proportion of adults scoring 2 or 3 on specific PHQ9 symptoms over time, NHANES 2005–2016

Symptom	2005–2006 n=4799	2007–2008 n= 5415	2009–2010 n= 5546	2011–2012 n= 4925	2013–2014 n= 5372	2015–2016 n= 5134	Odds Ratio (2005/06 vs. 2015/16)
							Odds Ratio [95% CI]	p value
1. Anhedonia	6.3%	7.4%	8.6%	8.4%	9.9%	9.6%	1.48 [1.27–1.73]	<.001
2. Feel depressed	6.1%	8.0%	8.1%	7.4%	7.7%	7.2%	1.12 [0.95–1.33]	.163
3. Sleep disturbance	12.5%	17.2%	17.0%	15.1%	15.8%	15.0%	1.21 [1.07–1.36]	0.002
4. Fatigue	14.4%	17.5%	16.5%	15.6%	17.0%	17.5%	1.26 [1.12–1.41]	<.001
5. Appetite	6.8%	9.4%	9.5%	9.2%	9.7%	9.3%	1.37 [1.17–1.59]	<.001
6. Guilt/worthlessness	3.8%	6.2%	5.8%	6.1%	6.0%	5.5%	1.37 [1.13–1.67]	.002
7. Concentration	4.5%	5.8%	6.1%	6.2%	7.1%	6.1%	1.28 [1.07–1.54]	.008
8. Hypoactivity/Hyperactivity	2.6%	4.0%	4.0%	4.4%	4.4%	3.8%	1.32 [1.04–1.67]	.022
9. Self-harm	0.9%	1.3%	1.1%	1.4%	1.2%	1.3%	1.29 [0.87–1.91]	.201