Table 3:

HRpQCT and Micro-FEA in African American and White adolescents and young adults with obesity.

	African American	White	p-Value	p-Value adjusted for height and sex
Distal Radius	N=20	N=38
Volumetric BMD (vBMD)
Total vBMD (mg HA/cm³)	354.8±54.6	359.9±69.0	0.774	0.704
Cortical vBMD (mg HA/cm³)	841.7 (804.3–886.9) ^*	832.8 (790.4–890.1) ^*	0.980	0.939
Trabecular vBMD (mg HA/cm³)	200.1±34.7	203.9±36.2	0.702	0.723
Bone Geometry
Total area (mm²)	282.2±53.5	267.1±54.9	0.319	0.049
Cortical area (mm²)	62.8±14.5	59.1±13.9	0.338	0.230
Trabecular area (mm²)	219.4±54.6	208.0±59.6	0.480	0.175
Cortical thickness (mm)	1.05±0.17	0.98±0.21	0.196	0.760
Bone Microarchitecture
Cortical pore volume (mm³)	9.01 (4.57–11.22) ^*	7.05 (4.51–11.73) ^*	0.556	0.181
Cortical porosity (%)	1.54 (0.79–1.95) ^*	1.15 (0.94–1.79) ^*	0.806	0.473
Cortical pore diameter (mm)	0.15 (0.14–0.16) ^*	0.14 (0.14–0.15) ^*	0.022	0.074
Trabecular number (1/mm)	2.19±0.29	2.26±0.27	0.375	0.356
Trabecular thickness (mm)	0.08±0.01	0.08±0.01	0.768	0.749
Trabecular separation (mm)	0.39±0.06	0.37±0.06	0.366	0.362
Strength Estimates
Stiffness (kN/mm)	94.5±17.8	87.1±16.1	0.116	0.031
Failure load (kN)	4.74±0.87	4.42±0.81	0.172	0.047

Distal Tibia	N=17	N=41
Volumetric BMD (vBMD)
Total vBMD (mg HA/cm³)	351.0±39.8	356.5±55.3	0.712	0.669
Cortical vBMD (mg HA/cm³)	888.3 (868.7–910.1) ^*	875.9 (846.9–888.3) ^*	0.028	0.012
Trabecular vBMD (mg HA/cm³)	212.2±33.5	223.0±29.8	0.232	0.291
Bone Geometry
Total area (mm²)	759.2±110.4	727.7±131.8	0.381	0.160
Cortical Area (mm²)	152.2±29.3	143.9±29.1	0.259	0.317
Trabecular Area (mm²)	607.7±108.1	583.8±139.4	0.530	0.306
Cortical thickness (mm)	1.31 (1.17–1.59) ^*	1.31 (1.05–1.48) ^*	0.344	0.792
Bone Microarchitecture
Cortical pore volume (mm³)	38.6±31.1	42.5±27.6	0.637	0.597
Cortical porosity (%)	2.94±1.87	3.57±1.95	0.247	0.172
Cortical pore diameter (mm)	0.15 (0.14–0.16) ^*	0.14 (0.14–0.15)	0.116	0.273
Trabecular Number (1/mm)	2.52 (2.16–2.66) ^*	2.60 (2.38–2.82) ^*	0.064	0.028
Trabecular Thickness (mm)	0.07 (0.07–0.09) ^*	0.07 (0.07–0.08) ^*	0.365	0.216
Trabecular Separation (mm)	0.33 (0.31–0.39) ^*	0.31 (0.29–0.36) ^*	0.076	0.027
Strength Estimates
Stiffness (N/mm)	264.2±39.9	248.8±32.1	0.120	0.052
Failure load (N)	13.4±2.0	12.6±1.6	0.132	0.048

Means ± SD;

Median (interquartile range)

For unadjusted analysis, the Student t-test was used to compare the two groups when data were normally distributed, and the Wilcoxon test was used when at least one of the groups was not normally distributed

Multivariate regression analyses were used to compare groups after adjusting for height and sex