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. 2020 Jun 23;140(3):317–339. doi: 10.1007/s00401-020-02178-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Human tau-induced downregulation of SFPQ in HeLa cells detected by immunoblotting. a–d Representative immunoblot images for tau, p-tau, SFPQ and TIA-1 after transient transfection of WT-tau or P301L-tau in HeLa cells. Densitometric analysis was performed with Lab image software. Statistical significance was estimated with one-way ANOVA and Tukey post-hoc test for multiple comparisons, *p < 0.05