Table 4.
Factors predictive of early deterioration using univariate and multivariate analyses in non-septic infected patients (SOFA score < 2) at inclusion (T0) (n = 223)
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| p value | IQR OR [95% CI] | p value | IQR OR [95% CI] | |
| Lactates | ns | – | ns | – |
| CRP | ns | – | ns | – |
| qSOFA score | ns | – | ns | – |
| Age | 0.0042 | 1.27 [1.08–1.51] | ns | – |
| Charlson score | 0.0029 | 1.25 [1.08–1.44] | ns | – |
| PCT | ns | – | ns | – |
| sUPAR | 0.022 | 1.49 [1.06–2.10] | ns | – |
| sVEGFR2 | 0.0002 | 2.76 [1.68–4.75] | 0.0017 | 2.35 [1.41–4.12] |
| sUPAR -sVEGFR2 combination | 0.0005 | 1.74 [1.28–2.41] | 0.019 | 1.52 [1.07–2.19] |
CRP C-reactive protein, qSOFA quick Sequential Organ Failure Assessment, PCT procalcitonin, IQR interquartile, OR odds ratio, CI confidence interval