Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 6;8:744. doi: 10.3389/fcell.2020.00744

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Cheng, Xu, Yu, Xu and Long.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The Xist/miR-32-5p axis exerts its role in angiogenesis by regulating Notch-1 expression. (A) The expression of Xist in HUVECs under hypoxic condition was quantitated by RT-qPCR. (B) HUVECs were exposed to different treatments. The expression of Notch-1 in HUVECs following transfection was quantitated by RT-qPCR. (C) The expression of Hes-1 following transfection was quantitated by RT-qPCR. Three independent experiments were carried out. ***p < 0.001, ****p < 0.0001 compared with the control group; ^###p < 0.001, ^####p < 0.0001 compared with the hypoxia group. Data are expressed as the mean ± SEM. (D) Diagram of the angiogenesis process after CCSCI. (E) The hypothetical function of Xist in hypoxia-induced angiogenesis in the current study.