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. 2020 Jun 8;140(3):405–407. doi: 10.1007/s00401-020-02169-z

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© The Author(s) 2020

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Fig. 1 — a Genomic copy number profile and b allele distribution (MIP) of a RELA-EP showing chromothripsis of chromosome 11; c case with homozygous CDKN2A deletion; d case showing breaks in C11orf95 (green bar) and RELA (red bar); e clear cell morphology; f nuclear p65-RelA; g case with homozygous CDKN2A deletion/loss of p16 protein (arrow, endothelial cell as internal positive control); h case without CDKN2A deletion/retained p16; i–k Kaplan–Meier analysis, impact of CDKN2A deletions on OS