Table 1.
Baseline characteristics of the 766 individuals of Tehran cardio-metabolic genetic study with 15 years follow up.
| Variable* | MHO | MUO | P-value** | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Female | Male | Total | Female | Male | Total | Female | Male | Total | |
| Participant, n (%) | 169 (82) | 37 (18) | 206 | 378 (67.5) | 182 (32.5) | 560 | < 0.001 | < 0.001 | ND |
| Age (year) | 30 ± 8 | 27 ± 8 | 29 ± 8 | 36 ± 10 | 34 ± 11 | 35 ± 10 | < 0.001 | 0.02 | < 0.001 |
| FPG (mg/dl) | 84 ± 7 | 86 ± 6 | 85 ± 7 | 87 ± 11 | 88 ± 6 | 87 ± 9 | < 0.001 | NS | < 0.001 |
| SBP (mmHg) | 105 ± 9 | 108 ± 7 | 106 ± 8 | 111 ± 11 | 112 ± 14 | 111 ± 12 | < 0.001 | NS | < 0.001 |
| DBP (mmHg) | 71 ± 7 | 69 ± 8 | 70 ± 7 | 74 ± 7 | 73 ± 9 | 74 ± 8 | < 0.001 | NS | < 0.001 |
| TG (mg/dl) | 86 ± 32 | 97 ± 33 | 88 ± 32 | 110 ± 42 | 124 ± 57 | 115 ± 51 | < 0.001 | NS | < 0.001 |
| HDL (mg/dl) | 51 ± 11 | 45 ± 6 | 50 ± 10 | 47 ± 11 | 43 ± 8 | 46 ± 10 | < 0.001 | NS | < 0.001 |
| WC (cm) | 80 ± 7 | 90 ± 9 | 82 ± 8 | 86 ± 7 | 89 ± 7 | 87 ± 7 | < 0.001 | NS | < 0.001 |
| BMI (kg/m2) | 27 ± 2 | 27 ± 3 | 27 ± 2 | 28 ± 2 | 27 ± 2 | 28 ± 2 | < 0.001 | NS | < 0.001 |
| HOMA-IR | 1.6 ± 0.77 | 1.9 ± 0.8 | 1.7 ± 0.78 | 1.8 ± 1.01 | 1.79 ± 1.00 | 1.8 ± 1.00 | 0.04 | NS | NS |
| IR, n (%) | 10 (5.9) | 5 (13.5) | 15 (7.3) | 44 (11.6) | 11 (6.0) | 55 (9.8) | NS | NS | NS |
| Low physical activity (METS) | 28 (16.6) | 4 (10.8) | 32 (15.5) | 75 (19.8) | 37 (20.3) | 112 (20) | NS | NS | NS |
| Non-smoker, n (%) | 161 (95.3) | 30 (81) | 191(92.7) | 357 (94.4) | 137 (75.3) | 494 (92.2) | NS | 0.02 | 0.02 |
| Menopause, n (%) | 30 (17.8) | ND | 78 (20.6) | ND | NS | ND | ND | ||
MHO metabolic healthy obese; MUO metabolic unhealthy obese; FPG fasting plasma glucose; SBP systolic blood pressure; DBP diastolic blood pressure; TG triglyceride; HDL high density lipoprotein; WC waist circumference; BMI body mass index; HOMA-IR homeostatic model assessment of insulin resistance; IR, insulin resistance; NS not significant at 0.05 level; ND, not done.
*Variables expressed as means ± standard deviation or number of individuals (percentages).
**P-value related to comparing MHO and MUO groups using t-test / Chi Square test for quantitative / qualitative variables, respectively.