Table 2.
V–J combinations with asymmetric expression in the two groups.
| V Gene | J Gene | Normalized expression in SLE group | Normalized expression in control group | No. of positive control samples | No. of positive SLE samples |
|---|---|---|---|---|---|
| TRBV11-1 | TRBJ1-1 | 88.2 ± 15.6 | – | 0 | 3 |
| TRBV12-5 | TRBJ2-1 | 128.6 ± 295.1 | – | 0 | 3 |
| TRBV25-1 | TRBJ2-3 | 100.9 ± 8.2 | – | 0 | 4 |
| TRBV27 | TRBJ1-1 | 300.7 ± 7.6 | – | 0 | 3 |
| TRBV4-1 | TRBJ2-5 | 184.1 ± 41.2 | – | 0 | 3 |
| TRBV5-5 | TRBJ1-6 | 56.2 ± 7.2 | – | 0 | 3 |
| TRBV6-9 | TRBJ2-7 | 35.9 ± 2.6 | – | 0 | 3 |
| TRBV7-6 | TRBJ1-5 | 146.9 ± 24.2 | – | 0 | 4 |
| TRBV7-8 | TRBJ2-2 | 163.4 ± 14.0 | – | 0 | 3 |
| TRBV10-1 | TRBJ1-1 | – | 58.6 ± 6.6 | 3 | 0 |
| TRBV10-3 | TRBJ2-6 | – | 77.4 ± 5.4 | 5 | 0 |
| TRBV12-3 | TRBJ1-4 | – | 117.6 ± 3.4 | 3 | 0 |
| TRBV12-3 | TRBJ2-2 | – | 567.3 ± 3.7 | 5 | 0 |
| TRBV12-4 | TRBJ1-4 | – | 50.4 ± 6.6 | 3 | 0 |
| TRBV13 | TRBJ2-1 | – | 43.5 ± 5.3 | 3 | 0 |
| TRBV14 | TRBJ2-2 | – | 132.4 ± 5.7 | 4 | 0 |
| TRBV28 | TRBJ1-6 | – | 246.1 ± 6.9 | 3 | 0 |
| TRBV3-1 | TRBJ2-2 | – | 698.9 ± 2.8 | 3 | 0 |
| TRBV3-1 | TRBJ2-5 | – | 34.0 ± 3.5 | 3 | 0 |
| TRBV5-5 | TRBJ1-4 | – | 75.1 ± 6.0 | 3 | 0 |
| TRBV6-4 | TRBJ1-1 | – | 2163.4 ± 7.3 | 6 | 0 |
The V–J combinations listed above are widely expressed (n ≥ 3) in one group while not expressed at all in the other group.