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. 2020 Aug 6;8:739. doi: 10.3389/fcell.2020.00739

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Copyright © 2020 Carmona, Guerrero, Jimenez, Ariza, Agüera, Obrero, Noci, Muñoz-Castañeda, Rodríguez, Soriano, Moreno, Martin-Malo and Aljama.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative histogram and quantification of microvesicles (MV/μl) in plasma by flow cytometry. The results are represented as the means ± SEM. (A) Number of microvesicles per microliter (Log Annexin V + MV) in elderly subjects, CKD4-5, hemodialysis and kidney transplantation patients. (B) Number of microvesicles per microliter (Log CD14 + Annexin V + MV) in elderly subjects, CKD4-5, hemodialysis and kidney transplantation patients. (C) Number of microvesicles per microliter (Log CD14 + Annexin V + CD16 + MV) in elderly patients, CKD4-5, hemodialysis and kidney transplantation patients. The data were analyzed using an ANOVA test and Post hoc Bonferroni to evaluate statistical significance between groups. p-value < 0.05 was considered on the borderline of statistical significance. *p ≤ 0.03 vs. elderly subjects; ^†p < 0.001vs. all groups.