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. 2020 Aug 6;8:776. doi: 10.3389/fbioe.2020.00776

Table 3.

The three most used materials (alginate, gelatin, GelMA, and its combinations in pairs) with its different cross-linking methods.

Material Chemical Physical Thermal References
Alginate C1 Campbell et al., 2015; Markstedt et al., 2015; Narayanan et al., 2016; Freeman and Kelly, 2017; Naghieh et al., 2018; Wu Y. et al., 2018
C1/C2 Khalil and Sun, 2009
C1/C5 Kundu et al., 2015
C2 Jia et al., 2014; Izadifar et al., 2016; Apelgren et al., 2017; Kosik-Kozioł et al., 2017; Nguyen et al., 2017; Polley et al., 2017; Schütz et al., 2017; Ahlfeld et al., 2018; Habib et al., 2018; He et al., 2018; Maiullari et al., 2018; Yu et al., 2018; Gonzalez-Fernandez et al., 2019
P4 Jeon et al., 2019
C3 Yang et al., 2017; Datta et al., 2018; Gao et al., 2018; Raddatz et al., 2018
C4 Bakarich et al., 2014; Gao et al., 2015, 2017; Li et al., 2017
C5 Hafeez et al., 2018; Aydogdu et al., 2019; Wei et al., 2019
C6 Yoon et al., 2019
C7 P1 Ji et al., 2019
P2 Ooi et al., 2018
Gelatin C1 Yan et al., 2018
C5 Irvine et al., 2015; Choi et al., 2018
T1 Tijore et al., 2018b
C6 Shin et al., 2018
C7 P3 AnilKumar et al., 2019
T1 Tijore et al., 2018a
T4 Xu X. et al., 2018
GelMA C7 P1 Ersumo et al., 2016
P2 Schuurman et al., 2013; Mouser et al., 2016; Levato et al., 2017; Celikkin et al., 2018; Zhou et al., 2019
P3 Bertassoni et al., 2014
P4 Billiet et al., 2014; Du et al., 2015; Suntornnond et al., 2017; Gu et al., 2018; Li et al., 2018cb; Pepelanova et al., 2018
Alginate Gelatin C2 Wang et al., 2016; Ding et al., 2017, 2018
T4 Giuseppe et al., 2017; Bandyopadhyay et al., 2018
C2/C1 T2 Berg et al., 2018
C3 Li et al., 2018c
C3/C5 Akkineni et al., 2016
C4 Chung et al., 2013
T3 He et al., 2016
C6 Aljohani et al., 2018
Alginate GelMA C1 P2 Daly et al., 2016b
P4 Daly et al., 2016a; Liu et al., 2018
C2 P3 Zhang X. et al., 2018
P4 Kosik-Kozioł et al., 2019; Krishnamoorthy et al., 2019
C4 P4 Costantini et al., 2016
C7 P2 Kang et al., 2017
P4 García-Lizarribar et al., 2018
Gelatin GelMA C5 P2 Haring et al., 2019
C8 P2 McBeth et al., 2017

Codification is at follows: C for Chemical crosslinking: C1: <100 mM Ca2+ solution, C2: [100–500] mM Ca2+ solution, C3: ≥500 mM Ca2+ solution, C4: Not given concentration of Ca2+ solution, C5: Other solute solution, C6: No available details for chemical crosslinking, and C7: No chemical crosslinking. P for Physical crosslinking: P1: 405 nm UV light, P2: 365 nm UV light, P3: UV light (special wavelength), P4: UV light (no data of wavelength). T for Thermal Crosslinking: T1: 37 °C, T2: Room temperature, T3: Special temperature, T4: no available details of thermal crosslinking.