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. 2020 Aug 6;10:1172. doi: 10.3389/fonc.2020.01172

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Copyright © 2020 Zhao, Liang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation and function of DLX6-AS1 in malignant behaviors of prostate cancer cells. DLX6-AS1 downregulates the expression of LARGE through the recruitment of DNMT1 to LARGE promoter and inducing its methylation, to accelerate proliferation, invasion, and metastasis of prostate cancer cells.