Table 1.
Application of a ketogenic diet in children with super-refractory status epilepticus in pediatric intensive care units (large series).
| Patients (n) | Age (years) | Sex (n) (F/M) | Route of KD (n) (enteral/intravenous) | FIRES (n) | Lag from SE onset to KD (n) (≦14 days) | Acute effects (response/poor response) (n) | |
|---|---|---|---|---|---|---|---|
| Nabbout [4] | 9 | 5.2–8.2 | 5/4 | 9/0 | 9 | 3 | 7/2 |
| Caraballo [47] | 10 | 0.5–16 | 4/6 | 10/0 | 2 | NR | 7/3 |
| Appavu [12] | 10 | 2–16 | 4/6 | 9/1 | 2 | 5 | 9/1 |
| Farias-Moeller [10] | 9 | 2–8 | 6/3 | 7/2 | 7 | 5 | 6/3 |
| Arya [46] | 14 | 0.4–19 | NR | 11/3 | 1 | 9 | 11/3 |
| Park [8] | 14 | 0.1–15 | 5/9 | 14/0 | 8 | 6 | 14/0 |
| Peng [49] | 7 | 1.5–13 | 3/4 | 5/2 | 7 | 4 | 7/0 |
| Arayakarnkul [48] | 13 | 0.2–13.5 | 6/7 | 8/5 | 3 | NR | 12/1 |
Abbreviations: F: female; M: male; KD: ketogenic diet; FIRES: febrile infection-related epilepsy syndrome; SE: status epilepticus; NR: not reported;
Park: We excluded two adult patients from this study; Arayakarnkul: We excluded four patients without ketogenic diet therapy from this study.