Subject | Analytical Chemistry |
Specific subject area | Toxicology, Public Health |
Type of data | Tables of raw data showing peak area from HPLC, adjustment for internal standard, associated concentration on calibration curve, and final calculation for each sample. Tables of absolute values, averages, SDs and % RSD of Food, Drug, & Cosmetic (FD&C) dyes in children vitamins and over-the-counter medications (OTCs) marketed for children and pregnant women. |
How data were acquired | Dyes were obtained using an InfinityLab Poroshell 120 EC-C18 column (250 mm × 4.6 mm, i.d. with 4 μm particle diameter, Agilent Technologies, Memphis, TN) on an Agilent 1200 HPLC system coupled with a photodiode array (PDA) detector (Agilent Technologies, Memphis, TN). Software: ChemStation Rev. B.04.03 |
Data Format | Raw Data |
Parameters for data collection | Three to five brands of children's gummy vitamins, children's tablet vitamins, prenatal vitamins, children's cough/cold/allergy tablets & syrups, and children's pain reliever tablets & syrups were collected across three U.S. states (California, Indiana, and Georgia) were sampled in varying flavors/colors, if possible. Three different lots, with differing expiration dates, of each brand were selected for sample replication. Each lot was extracted in duplicate. |
Description of data collection | A composite sample was created for each lot of each brand and the sample was diluted in water, then sonicated until homogenous. The sample was centrifuged before being concentrated and washed on a solid phase extraction (SPE) column. The final sample collected was dried in a Speed Vac and reconstituted in water to be quantified using HPLC-PDA. |
Data source location | University of California-Davis, Davis, California |
Data accessibility | Repository Name: Mendeley Data Data identification number: 10.17632/n6m7rhct2h.1 Direct URL to data: http://dx.doi.org/10.17632/n6m7rhct2h.1 |
Related research article | Lehmkuhler, M. Miller, A. Bradman, R. Castroina, A. Mitchell, Quantification of Certified Food Dyes in Over the Counter Medicines and Supplements Marketed for Children and Pregnant Women. In press. |