Table 3.
Associations of Region of Birth With Global Cognition and the Five Cognitive Domains
| Global cognition | Episodic memory | Semantic memory | Working memory | Perceptual speed | Visuospatial ability | |
|---|---|---|---|---|---|---|
| Age | −0.02 | −0.03 | −0.02 | −0.01 | −0.04 | −0.02 |
| (0.003, p < .0001) | (0.004, p < .0001) | (0.004, p < .0001) | (0.005, p = .04) | (0.004, p < .0001) | (0.005, p < .0001) | |
| Sex | −0.07 | −0.17 | −0.03 | −0.03 | −0.15 | 0.28 |
| (0.04, p = .10) | (0.06, p = .004) | (0.06, p = .63) | (0.07, p = .62) | (0.06, p = .01) | (0.07, p = .002) | |
| Education | 0.05 | 0.03 | 0.06 | 0.05 | 0.06 | 0.05 |
| (0.006, p < .0001) | (0.007, p < .0001) | (0.008, p < .0001) | (0.009, p < .0001) | (0.007, p < .0001) | (0.008, p < .0001) | |
| BMI | −0.003 | 0.001 | −0.007 | −0.005 | −0.0001 | −0.006 |
| (0.003, p = .45) | (0.004, p = .80) | (0.004, p = .12) | (0.005, p = .31) | (0.004, p = .84) | (0.004, p = .23) | |
| CVD-RF burden | 0.01 | 0.03 | −0.03 | 0.04 | 0.004 | −0.04 |
| (0.02, p = .65) | (0.03, p = .34) | (0.03, p = .36) | (0.03, p = .26) | (0.03, p = .90) | (0.03, p = .25) | |
| South born | −0.22 | −0.13 | −0.33 | −0.20 | −0.35 | −0.25 |
| (0.04, p < .0001) | (0.05, p = .01) | (0.05, p < .0001) | (0.06, p = .001) | (0.05, p < .0001) | (0.06, p < .0001) | |
| Time*age | −0.004 | −0.004 | −0.005 | −0.003 | −0.003 | −0.002 |
| (0.001, p < .0001) | (0.001, p = .002) | (0.001, p < .0001) | (0.001, p = .0004) | (0.001, p < .0001) | (0.001, p = .001) | |
| Time*sex | −0.02 | −0.03 | −0.01 | −0.02 | −0.001 | −0.006 |
| (0.01, p = .07) | (0.01, p = .02) | (0.01, p = .23) | (0.01, p = .09) | (0.009, p = .92) | (0.009, p = .51) | |
| Time*education | −0.002 | −0.003 | −0.003 | −0.0001 | −0.001 | 0.001 |
| (0.001, p = .14) | (0.002, p = .12) | (0.002, p = .11) | (0.001, p = .80) | (0.001, p = .41) | (0.001, p = .61) | |
| Time*BMI | 0.001 | 0.001 | 0.001 | 0.002 | 0.001 | 0.001 |
| (0.001, p = .16) | (0.001, p = .50) | (0.001, p = .22) | (0.001, p = .07) | (0.001, p = .31) | (0.001, p = .46) | |
| Time*CVD−RF Burden | 0.009 | 0.01 | 0.02 | 0.003 | −0.0001 | 0.008 |
| (0.006, p = .11) | (0.007, p = .14) | (0.007, p = .003) | (0.006, p = .60) | (0.004, p = .94) | (0.004, p = .09) | |
| Time*South born | −0.007 | −0.004 | 0.003 | −0.01 | −0.005 | −0.006 |
| (0.01, p = .50) | (0.01, p = .79) | (0.01, p = .82) | (0.01, p = .15) | (0.008, p = .57) | (0.008, p = .43) |
Note: BMI = Body mass index; CVD-RF = cardiovascular disease risk factor. Values are unstandardized coefficient (SE, p-value) from linear regression models with significance corrected for multiple comparisons at p < .01. Bolded terms and values denote variables of interest for this study, not significance levels.