Table 2. Effect of AA on MPO Activity, Reduced Levels of GSH, and Concentration of MDA in the Peritoneal Exudatea.
|
parameters |
|||
---|---|---|---|---|
treatments | dose (mg/kg) | MPO (U/mL) | GSH (μg/mL) | MDA (nmol/mL) |
VEH | 3.30 ± 0.92 | 35.77 ± 2.51 | 2.19 ± 0.91 | |
carrageenan | 18.20 ± 1.28* | 20.62 ± 1.48* | 44.33 ± 4.71* | |
AA | 25 | 6.98 ± 0.87# | 32.32 ± 1.13# | 17.16 ± 3.32# |
MPO: myeloperoxidase; GSH: reduced glutathione; MDA: malondialdehyde. Values are mean ± SEM (n = 5) *p < 0.05 vs VEH group, #p < 0.05 vs carragenine (one-way ANOVA followed by Newman–Keuls test). VEH: vehicle; AA: anacardic acid.